6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one
| Nā ʻano kemika | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one he wai ʻaʻole waihoʻoluʻu a hiki i ka melemele māmā, hiki ʻole ke hoʻoheheʻe ʻia i ka wai, hiki ke hoʻoheheʻe ʻia i CHCl3, pono e hoʻopaʻa ʻia ka waiho ʻana, hoʻokaʻawale ʻia mai nā oxidants, nā kemika hiki ke ʻai ʻia, mai ke ahi, ke kumu wela. | |
| Nā noi | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-oneHe mea waena ia o Alectinib, he mea hoʻopaʻapaʻa anaplastic lymphoma kinase (ALK) i koho nui ʻia a hiki ke hoʻopaʻa i ka mutant kiaʻi puka kūʻokoʻa, e hopena i ka ulu ʻana o ke kelepona. | |
| ʻAno kino | Wai waihoʻoluʻu a melemele | |
| Ola ola | Wahi a kā mākou ʻike, hiki ke mālama ʻia ka huahana no 12mahina mai ka lā o ka lawe ʻana inā mālama ʻia i loko o nā pahu i hoʻopaʻa paʻa ʻia, pale ʻia mai ka mālamalama a me ka wela a mālama ʻia i nā mahana ma waena o 5 -30°C. | |
| Tmau waiwai
| Lae paila | 354.7±42.0 °C ma 760 mmHg |
| Lae Flash | 168.3±27.9 °C | |
| Misa pololei | 282.025543 | |
| PSA | 26.30000 | |
| LogP | 3.25 | |
| ʻO ke kaomi mahu | 0.0±0.8 mmHg ma 25°C | |
| Index of Refraction | 1.545 | |
| pka | 1.26±0.10(Wanamua) | |
| Hiki i ka wai | 50 mg/ml ma CHCl3 | |
Palekana
I ka lawelawe ʻana i kēia huahana, e ʻoluʻolu e hoʻokō i ka ʻōlelo aʻoaʻo a me ka ʻike i hāʻawi ʻia ma ka pepa ʻikepili palekana a e nānā i nā ana palekana palekana a me nā wahi hana i kūpono no ka lawelawe ʻana i nā kemika.
Nānā
Hoʻokumu ʻia nā ʻikepili i loko o kēia puke i ko mākou ʻike a me kā mākou ʻike i kēia manawa.Ma muli o nā kumu he nui e pili ana i ka hana ʻana a me ka hoʻohana ʻana i kā mākou huahana, ʻaʻole e hoʻokuʻu kēia mau ʻikepili i nā mea hana mai ka hana ʻana i kā lākou mau noiʻi a me nā hoʻāʻo;ʻAʻole hoʻi i hōʻike kēia mau ʻikepili i ka hōʻoiaʻiʻo o kekahi mau waiwai, a i ʻole ke kūpono o ka huahana no kahi kumu kikoʻī.ʻO nā wehewehe, nā kiʻi, nā kiʻi, nā ʻikepili, nā ʻāpana, nā kaupaona, a me nā mea ʻē aʻe i hāʻawi ʻia ma ʻaneʻi hiki ke hoʻololi me ka ʻole o ka ʻike mua a ʻaʻole ia e lilo i ka maikaʻi aelike o ka huahana.ʻO ka maikaʻi aelike o ka huahana i loaʻa wale mai nā ʻōlelo i hana ʻia ma ka kikoʻī huahana.ʻO ia ke kuleana o ka mea i loaʻa i kā mākou huahana e hōʻoia i ka mālama ʻia ʻana o nā kuleana kuleana a me nā kānāwai a me nā kānāwai e kū nei.
